Chlorpheniramine
is an anti-histamine inhibits link histamine H 1 receptors are
competitive reversible. Reduces vasodilation on Balhustamin and
increased capillary permeability. Is well absorbed after giving oral and widely distributed all over the body, including the central nervous system. Used for cases of upper respiratory allergy include sinusitis, conjunctivitis, dermatitis, nausea, vomiting and calm.
Uses
Episodic treatment for:Urticaria.Severe itchingContraindications
Sensitivity for Klorvinamin or materials used in the compound.Closed angle glaucoma,Bladder neck obstruction,Symptoms of an enlarged prostate,During acute asthma attacksNewbornsBreastfeedingSimultaneous use with Monoamine Alooxidaz inhibitors.Precautions
Hyper thyroid: anti effects may be predisposed to choline receptors for antihistamines, used with caution.Heart Disease: Use with caution in heart disease such as ischemic heart disease and high blood pressure.Enlarged prostate / urinary blockage: used with caution.
Older Persons: at least use the dose because of side effects, eg: dizziness, drowsiness and confusion vision, low blood pressure and susceptibility to fall and fracture.Respiratory diseases: used with caution in patients who suffer from asthma or other chronic breathing disorders and is not used during an asthma attack.
Children under two years: sedative antihistamines are not given to children under two years, but after consultation with specialists, because the safety of such use is not documented. And sedative antihistamines have antifungal activity important Mscaren: So do not give it to newborns and their use with caution in children with urinary retention, glaucoma, or disability.
This medication may cause drowsiness and makes it difficult to operate machinery or driving a car.Avoid alcohol or any other drug may cause calm.Porphyria, more antihistamines should avoid them in porphyria, but some believe that they are safe for use.Hepatic weakness, it is necessary to reduce the dose in the case of kidney weakness. Antihistamines Almnash must be avoid them in patients with acute liver disease, because of the increased risk of coma.
For use in pregnancy: the safety of its use in pregnancy has not been confirmed. Must use Klorvinramen only when the need of the mother outweigh any possible risks or possible the fetus.Breastfeeding: Do not use during lactation.Side effects
Common symptoms: dizziness, tinnitus, confusion vision, anxiety, insomnia, tremors, nausea, vomiting, constipation, diarrhea, harassment in the esophagus, dry mouth, cough.
Rare: urinary retention, palpitations, low blood pressure, headache, hallucination, mental disorder, anemia, allergic reaction, disorder, weak movement, polio, hepatitis. Paradoxical stimulation: stimulating the central nervous system may occur rarely, especially in children (excitement, hallucinations, ataxia, book) instead of calm.These drugs cause drowsiness.Exceeded dose: drowsiness, ataxia is the most common symptoms of acute dose exceeded.Effects anti Alkuliniat include expansion interpupillary high heat and get within two hours of taking the drug in serious cases get bouts followed by subsidence respiratory and cardiovascular, incitement vomiting or gastric lavage, which is given after charcoal tonic have value when given within a few hours of taking the drug. Otherwise, the symptomatic treatment aims to maintain breathing and control the seizures and impaired cardiovascular systems.Drug Interactions
Monoamine oxidase inhibitors (such as phenelzine), (do not use with Alkruvinramen)Tricyclic antidepressants (such as amitriptyline),Phenytoin,Drugs that act on the nervous system inhibition,Alcohol,Inhibitors of CYP3A4: may increase the levels / effects of chlorpheniramine. And include azole antifungals, ciprofloxacin, clarithromycin, diclofenac, doxycycline erythromycin, Aametinb, isoniazid, Nnifazodon, nicardipine, propofol, protease inhibitors, quinidine, and verapamil.Anticholinergic drugsDosage forms
Tablets: 4 mg, 8 mg.Solution for glaucoma: 10 mg / ml.Syrup: 2 mg / 5 ml, 2.5 mg / 5 mL.Chemical formula Molecular
C16H19ClN2Relative molecular mass (g / mol)
274.788Storage
You must save the drive well-closed containers away from light and humidity at a temperature of 2-25 degrees Celsius.
Uses
Episodic treatment for:Urticaria.Severe itchingContraindications
Sensitivity for Klorvinamin or materials used in the compound.Closed angle glaucoma,Bladder neck obstruction,Symptoms of an enlarged prostate,During acute asthma attacksNewbornsBreastfeedingSimultaneous use with Monoamine Alooxidaz inhibitors.Precautions
Hyper thyroid: anti effects may be predisposed to choline receptors for antihistamines, used with caution.Heart Disease: Use with caution in heart disease such as ischemic heart disease and high blood pressure.Enlarged prostate / urinary blockage: used with caution.
Older Persons: at least use the dose because of side effects, eg: dizziness, drowsiness and confusion vision, low blood pressure and susceptibility to fall and fracture.Respiratory diseases: used with caution in patients who suffer from asthma or other chronic breathing disorders and is not used during an asthma attack.
Children under two years: sedative antihistamines are not given to children under two years, but after consultation with specialists, because the safety of such use is not documented. And sedative antihistamines have antifungal activity important Mscaren: So do not give it to newborns and their use with caution in children with urinary retention, glaucoma, or disability.
This medication may cause drowsiness and makes it difficult to operate machinery or driving a car.Avoid alcohol or any other drug may cause calm.Porphyria, more antihistamines should avoid them in porphyria, but some believe that they are safe for use.Hepatic weakness, it is necessary to reduce the dose in the case of kidney weakness. Antihistamines Almnash must be avoid them in patients with acute liver disease, because of the increased risk of coma.
For use in pregnancy: the safety of its use in pregnancy has not been confirmed. Must use Klorvinramen only when the need of the mother outweigh any possible risks or possible the fetus.Breastfeeding: Do not use during lactation.Side effects
Common symptoms: dizziness, tinnitus, confusion vision, anxiety, insomnia, tremors, nausea, vomiting, constipation, diarrhea, harassment in the esophagus, dry mouth, cough.
Rare: urinary retention, palpitations, low blood pressure, headache, hallucination, mental disorder, anemia, allergic reaction, disorder, weak movement, polio, hepatitis. Paradoxical stimulation: stimulating the central nervous system may occur rarely, especially in children (excitement, hallucinations, ataxia, book) instead of calm.These drugs cause drowsiness.Exceeded dose: drowsiness, ataxia is the most common symptoms of acute dose exceeded.Effects anti Alkuliniat include expansion interpupillary high heat and get within two hours of taking the drug in serious cases get bouts followed by subsidence respiratory and cardiovascular, incitement vomiting or gastric lavage, which is given after charcoal tonic have value when given within a few hours of taking the drug. Otherwise, the symptomatic treatment aims to maintain breathing and control the seizures and impaired cardiovascular systems.Drug Interactions
Monoamine oxidase inhibitors (such as phenelzine), (do not use with Alkruvinramen)Tricyclic antidepressants (such as amitriptyline),Phenytoin,Drugs that act on the nervous system inhibition,Alcohol,Inhibitors of CYP3A4: may increase the levels / effects of chlorpheniramine. And include azole antifungals, ciprofloxacin, clarithromycin, diclofenac, doxycycline erythromycin, Aametinb, isoniazid, Nnifazodon, nicardipine, propofol, protease inhibitors, quinidine, and verapamil.Anticholinergic drugsDosage forms
Tablets: 4 mg, 8 mg.Solution for glaucoma: 10 mg / ml.Syrup: 2 mg / 5 ml, 2.5 mg / 5 mL.Chemical formula Molecular
C16H19ClN2Relative molecular mass (g / mol)
274.788Storage
You must save the drive well-closed containers away from light and humidity at a temperature of 2-25 degrees Celsius.
